When Low Blood Sugar Hits Hard: Rethinking Hypoglycemia’s Hidden Costs

- Tirzepatide & counterregulation – Pieber et al. show tirzepatide preserves glucagon response during hypoglycemia in type 2 diabetes, with notable hormonal changes.

- CGM in surgery – Carlier et al. review perioperative continuous glucose monitoring, highlighting overall accuracy but technical challenges intraoperatively.

- Diabetes & dementia risk – Tabesh et al. link hypoglycemia and poor glycemic control with higher dementia and cognitive decline risks in type 2 diabetes.

- Nitric oxide & brain health – Siervo et al. identify inorganic nitrate in astrocytes as a potential neuroprotective mechanism under hypoxia.

- Neonatal mortality in Africa – Jena & Jaldo find preterm birth and low birth weight are major mortality drivers, underscoring maternal health gaps.

- Herbal medicine efficacy – Li et al. review ginger, turmeric, and other herbal remedies, finding modest HbA1c reductions but stressing caution as adjuncts.

- Smart Snack app – Mosquera-Lopez et al. show a bedtime app intervention reduced severe nocturnal hypoglycemia in type 1 diabetes.

- Insulin icodec app adherence – Bajaj et al. report strong adherence to app-based dosing support for once-weekly insulin in treatment-naïve patients.

- Real-world CGM switch – Chu & Abitbol demonstrate improved HbA1c and time-in-range after moving from flash to real-time CGM in adults with type 1 diabetes.

- Long-term iGlarLixi outcomes – Malik et al. confirm sustained 0.9% HbA1c reduction over 24 months with stable weight in U.S. type 2 diabetes patients.