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The 10-Week Warning: Predicting Gestational Diabetes Before It Starts

Rethinking Diabetes: A Weekly Review

Malattie Metaboliche e Diabetologia

The 10-Week Warning: Predicting Gestational Diabetes Before It Starts

This week on Rethinking Diabetes, we explore a major discovery linking low PAPP-A levels in early pregnancy to a 75% higher risk of gestational diabetes — and what that means for early intervention. From metabolic “vicious cycles” to cutting-edge assays and the post-COVID rise in complications, this episode connects the latest findings across reproductive health, immunology, and metabolic science to spotlight a more personalized future for diabetes care.

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Bibliography

-Shyu IL, Tsai YC, Kuo TN, Shiue YL. Prognostic impact of pregnancy-associated plasma protein-A (PAPP-A) for gestational diabetes mellitus (GDM): an updated systematic review and meta-analysis of more than 90 000 pregnancies. Am J Reprod Immunol. 2025;93(6):e70087. doi:10.1111/aji.70087.


- Yang T, Luo L, Luo X, Liu X. Metabolic crosstalk and therapeutic interplay between diabetes and hyperuricemia. Diabetes Res Clin Pract. 2025;224:112204. doi:10.1016/j.diabres.2025.112204.


- Nierves LA, Lin TT, Moradian A, Shen Q, Sechi S, MacCoss MJ, et al. Biomarkers, proteoforms, and mass spectrometry-based assays for diabetes clinical research. J Clin Endocrinol Metab. 2025;110(6):1514-1523. doi:10.1210/clinem/dgaf159.


- Moiz A, Filion KB, Tsoukas MA, Yu OH, Peters TM, Eisenberg MJ. Mechanisms of GLP-1 receptor agonist-induced weight loss: a review of central and peripheral pathways in appetite and energy regulation. Am J Med. 2025;138(6):934-940. doi:10.1016/j.amjmed.2025.01.021.


- Thong PM, Wong YH, Kornfeld H, Goletti D, Ong CWM. Immune dysregulation of diabetes in tuberculosis. Semin Immunol. 2025;78:101959. doi:10.1016/j.smim.2025.101959.


- Gough KL, Dando SJ, Teasdale SL, Feigl B, Huygens F, Pelzer ES. Gut-associated metabolites and diabetes pathology: a systematic review. Front Endocrinol (Lausanne). 2025;16:1559638. doi:10.3389/fendo.2025.1559638.


- Moghdam Y, Arghavan B, Kermani F, Jeddi SA, Khojasteh S, Shokohi T, et al. A fatal post-COVID-19 sino-orbital mucormycosis in an adult patient with diabetes mellitus: a case report and review of the literature. J Infect Dev Ctries. 2025;19(5):661-668. doi:10.3855/jidc.16526.


- Cure E, Cumhur Cure M. Emerging risks of lipid-lowering therapy and low LDL levels: implications for eye, brain, and new-onset diabetes. Lipids Health Dis. 2025;24(1):185. doi:10.1186/s12944-025-02606-6.


- Kulecki M, Naskręt D, Uruska A, Zozulińska-Ziółkiewicz D. The nondipping blood pattern in type 1 diabetes mellitus: pathophysiology, complications, and management strategies. Endocr Pract. 2025;31(6):821-828. doi:10.1016/j.eprac.2025.02.015.


- Poluga J, Barać A, Katanić N, Milošević B, Nikolić N, Stevanović G, et al. SARS-CoV-2 associated encephalitis. J Infect Dev Ctries. 2025;19(5):649-653. doi:10.3855/jidc.19952.

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