Rethinking Diabetes: A Weekly Review
Malattie Metaboliche e Diabetologia
Vitamin D Controversies and Diabetes Innovations
This week's episode covers vitamin D controversies in metabolic health, cardiovascular benefits of semaglutide, advances in diabetes technology including hybrid closed-loop systems, and novel approaches to managing complications in diabetes and CKD.
Bibliography
1. Consensus statement on vitamin D role in metabolic health.
Authors: Giustina A, di Filippo L, Aleksova A, et al.
Journal: Metabolism: clinical and experimental, 2026 Mar
PMID: 41435994
DOI: 10.1016/j.metabol.2025.156484
2. Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.
Authors: Marso SP, Bain SC, Consoli A, et al.
Journal: The New England journal of medicine, 2016 Nov 10
PMID: 27633186
DOI: 10.1056/NEJMoa1607141
3. End Point-Based Threshold for the Ambulatory Arterial Stiffness Index.
Authors: Cheng YB, An DW, Zhang DY, et al.
Journal: Hypertension (Dallas, Tex. : 1979), 2026 Mar
PMID: 41503706
DOI: 10.1161/HYPERTENSIONAHA.125.25442
4. Cushing's disease and negative MRI: a single-center series, systematic literature review, and meta-analysis.
Authors: Ghidoni F, Madoglio A, Chiloiro S, et al.
Journal: Neurosurgical review, 2026 Feb 25
PMID: 41735650
DOI: 10.1007/s10143-026-04168-2
5. Insights for personalized choice of a hybrid closed-loop system: an expert opinion.
Authors: Di Molfetta S, Boscari F, Rossi A, et al.
Journal: Diabetes research and clinical practice, 2026 Mar
PMID: 41611094
DOI: 10.1016/j.diabres.2026.113120
6. Psychosocial outcomes among adults with type 1 diabetes using a tubeless automated insulin delivery system compared with sensor augmented pump therapy: A randomised, parallel-group clinical trial sub-study.
Authors: Riveline JP, Renard E, Aleppo G, et al.
Journal: Diabetes, obesity & metabolism, 2026 Mar
PMID: 41508715
DOI: 10.1111/dom.70416
7. Efficacy of probiotics (Bifidobacterium bifidum G9-1) in patients with type 2 diabetes mellitus and chronic kidney disease complicated by constipation: An exploratory, multicenter, open-label, single-arm study (BIRDIE study).
Authors: Ikeda F, Sato J, Yoshii H, et al.
Journal: Journal of diabetes investigation, 2026 Mar
PMID: 41504339
DOI: 10.1111/jdi.70236
8. Safety and efficacy of anticoagulant administration in people with atrial fibrillation and advanced chronic kidney disease.
Authors: Irlik K, Kwiendacz H, Ignacy W, et al.
Journal: Expert opinion on drug safety, 2026 Mar
PMID: 41292445
DOI: 10.1080/14740338.2025.2574492
9. Phase I Clinical Trial of Islet Antigen-Specific Plasmid Coexpressing Tolerogenic Proteins Demonstrates Safety in Adults With Type 1 Diabetes.
Authors: Greenbaum CJ, Long SA, Gitelman SE, et al.
Journal: Diabetes, 2026 Mar 1
PMID: 41564354
DOI: 10.2337/db25-0777
10. Micronutrient Deficiencies in the Era of Second-Generation Incretin-Based Therapies for Obesity.
Authors: Koceva A, Janež A, Pečko T, et al.
Journal: Nutrients, 2026 Feb 19
PMID: 41754194
DOI: 10.3390/nu18040677
Authors: Giustina A, di Filippo L, Aleksova A, et al.
Journal: Metabolism: clinical and experimental, 2026 Mar
PMID: 41435994
DOI: 10.1016/j.metabol.2025.156484
2. Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.
Authors: Marso SP, Bain SC, Consoli A, et al.
Journal: The New England journal of medicine, 2016 Nov 10
PMID: 27633186
DOI: 10.1056/NEJMoa1607141
3. End Point-Based Threshold for the Ambulatory Arterial Stiffness Index.
Authors: Cheng YB, An DW, Zhang DY, et al.
Journal: Hypertension (Dallas, Tex. : 1979), 2026 Mar
PMID: 41503706
DOI: 10.1161/HYPERTENSIONAHA.125.25442
4. Cushing's disease and negative MRI: a single-center series, systematic literature review, and meta-analysis.
Authors: Ghidoni F, Madoglio A, Chiloiro S, et al.
Journal: Neurosurgical review, 2026 Feb 25
PMID: 41735650
DOI: 10.1007/s10143-026-04168-2
5. Insights for personalized choice of a hybrid closed-loop system: an expert opinion.
Authors: Di Molfetta S, Boscari F, Rossi A, et al.
Journal: Diabetes research and clinical practice, 2026 Mar
PMID: 41611094
DOI: 10.1016/j.diabres.2026.113120
6. Psychosocial outcomes among adults with type 1 diabetes using a tubeless automated insulin delivery system compared with sensor augmented pump therapy: A randomised, parallel-group clinical trial sub-study.
Authors: Riveline JP, Renard E, Aleppo G, et al.
Journal: Diabetes, obesity & metabolism, 2026 Mar
PMID: 41508715
DOI: 10.1111/dom.70416
7. Efficacy of probiotics (Bifidobacterium bifidum G9-1) in patients with type 2 diabetes mellitus and chronic kidney disease complicated by constipation: An exploratory, multicenter, open-label, single-arm study (BIRDIE study).
Authors: Ikeda F, Sato J, Yoshii H, et al.
Journal: Journal of diabetes investigation, 2026 Mar
PMID: 41504339
DOI: 10.1111/jdi.70236
8. Safety and efficacy of anticoagulant administration in people with atrial fibrillation and advanced chronic kidney disease.
Authors: Irlik K, Kwiendacz H, Ignacy W, et al.
Journal: Expert opinion on drug safety, 2026 Mar
PMID: 41292445
DOI: 10.1080/14740338.2025.2574492
9. Phase I Clinical Trial of Islet Antigen-Specific Plasmid Coexpressing Tolerogenic Proteins Demonstrates Safety in Adults With Type 1 Diabetes.
Authors: Greenbaum CJ, Long SA, Gitelman SE, et al.
Journal: Diabetes, 2026 Mar 1
PMID: 41564354
DOI: 10.2337/db25-0777
10. Micronutrient Deficiencies in the Era of Second-Generation Incretin-Based Therapies for Obesity.
Authors: Koceva A, Janež A, Pečko T, et al.
Journal: Nutrients, 2026 Feb 19
PMID: 41754194
DOI: 10.3390/nu18040677
