Pediatric Frontiers: Weekly Insights
Pediatria
Neonatal and Pediatric Advances: From BPD to PKU
This week's episode covers groundbreaking research in neonatology and pediatrics, including bronchopulmonary dysplasia, PDA management, pediatric VTE, asthma biologics, congenital adrenal hyperplasia, and phenylketonuria.
Bibliography
1. Bronchopulmonary dysplasia: A review of pathogenesis and pathophysiology.
Authors: Kalikkot Thekkeveedu R, Guaman MC, Shivanna B
Journal: Respiratory medicine, 2017 Nov
PMID: 29229093
DOI: 10.1016/j.rmed.2017.10.014
2. Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen.
Authors: Gupta S, Subhedar NV, Bell JL, et al.
Journal: The New England journal of medicine, 2024 Jan 25
PMID: 38265644
DOI: 10.1056/NEJMoa2305582
3. Venous thromboembolism in pediatrics: Management of special clinical scenarios.
Authors: Climent FJ, Campo Palacio HJ, Falcón M, et al.
Journal: Anales de pediatria, 2026 Jul
PMID: 42457447
DOI: 10.1016/j.anpede.2026.504234
4. Switching to twice-yearly depemokimab from mepolizumab/benralizumab in severe asthma: a multicenter, randomized, double-blind, phase 3A clinical trial (NIMBLE).
Authors: Chupp G, Nagase H, Skowasch D, et al.
Journal: American journal of respiratory and critical care medicine, 2026 May 1
PMID: 41738176
DOI: 10.1093/ajrccm/aamag031
5. Congenital Adrenal Hyperplasia-Current Insights in Pathophysiology, Diagnostics, and Management.
Authors: Claahsen-van der Grinten HL, Speiser PW, Ahmed SF, et al.
Journal: Endocrine reviews, 2022 Jan 12
PMID: 33961029
DOI: 10.1210/endrev/bnab016
6. Phenylketonuria.
Authors: van Spronsen FJ, Blau N, Harding C, et al.
Journal: Nature reviews. Disease primers, 2021 May 20
PMID: 34017006
DOI: 10.1038/s41572-021-00267-0
Authors: Kalikkot Thekkeveedu R, Guaman MC, Shivanna B
Journal: Respiratory medicine, 2017 Nov
PMID: 29229093
DOI: 10.1016/j.rmed.2017.10.014
2. Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen.
Authors: Gupta S, Subhedar NV, Bell JL, et al.
Journal: The New England journal of medicine, 2024 Jan 25
PMID: 38265644
DOI: 10.1056/NEJMoa2305582
3. Venous thromboembolism in pediatrics: Management of special clinical scenarios.
Authors: Climent FJ, Campo Palacio HJ, Falcón M, et al.
Journal: Anales de pediatria, 2026 Jul
PMID: 42457447
DOI: 10.1016/j.anpede.2026.504234
4. Switching to twice-yearly depemokimab from mepolizumab/benralizumab in severe asthma: a multicenter, randomized, double-blind, phase 3A clinical trial (NIMBLE).
Authors: Chupp G, Nagase H, Skowasch D, et al.
Journal: American journal of respiratory and critical care medicine, 2026 May 1
PMID: 41738176
DOI: 10.1093/ajrccm/aamag031
5. Congenital Adrenal Hyperplasia-Current Insights in Pathophysiology, Diagnostics, and Management.
Authors: Claahsen-van der Grinten HL, Speiser PW, Ahmed SF, et al.
Journal: Endocrine reviews, 2022 Jan 12
PMID: 33961029
DOI: 10.1210/endrev/bnab016
6. Phenylketonuria.
Authors: van Spronsen FJ, Blau N, Harding C, et al.
Journal: Nature reviews. Disease primers, 2021 May 20
PMID: 34017006
DOI: 10.1038/s41572-021-00267-0
