Pediatric Frontiers: Weekly Insights
Pediatria
Gestational Diabetes, Autism Therapies, and Neonatal Care Updates
This week's episode covers metformin in gestational diabetes, autism spectrum disorder treatments, early motor milestone delays in neurodevelopmental conditions, and updates on PDA management in preterm infants.
Bibliography
1. Early Metformin in Gestational Diabetes: A Randomized Clinical Trial.
Authors: Dunne F, Newman C, Alvarez-Iglesias A, et al.
Journal: JAMA, 2023 Oct 24
PMID: 37786390
DOI: 10.1001/jama.2023.19869
2. Atypical antipsychotics for autism spectrum disorder: a network meta-analysis.
Authors: Meza N, Franco JV, Sguassero Y, et al.
Journal: The Cochrane database of systematic reviews, 2025 May 21
PMID: 40396498
DOI: 10.1002/14651858.CD014965.pub2
3. A systematic review and meta-analysis of the associations between motor milestone timing and motor development in neurodevelopmental conditions.
Authors: Bowler A, Arichi T, Austerberry C, et al.
Journal: Neuroscience and biobehavioral reviews, 2024 Dec
PMID: 39067834
DOI: 10.1016/j.neubiorev.2024.105825
4. Early Metformin in Gestational Diabetes: A Randomized Clinical Trial.
Authors: Dunne F, Newman C, Alvarez-Iglesias A, et al.
Journal: JAMA, 2023 Oct 24
PMID: 37786390
DOI: 10.1001/jama.2023.19869
5. Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants: The PDA Randomized Clinical Trial.
Authors: Laughon MM, Thomas SM, Watterberg KL, et al.
Journal: JAMA, 2026 Feb 17
PMID: 41364689
DOI: 10.1001/jama.2025.23330
6. Multisystem Inflammatory Syndrome in Children (MIS-C).
Authors: Patel JM
Journal: Current allergy and asthma reports, 2022 May
PMID: 35314921
DOI: 10.1007/s11882-022-01031-4
7. Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.
Authors: Armstrong PW, Pieske B, Anstrom KJ, et al.
Journal: The New England journal of medicine, 2020 May 14
PMID: 32222134
DOI: 10.1056/NEJMoa1915928
8. Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants: The PDA Randomized Clinical Trial.
Authors: Laughon MM, Thomas SM, Watterberg KL, et al.
Journal: JAMA, 2026 Feb 17
PMID: 41364689
DOI: 10.1001/jama.2025.23330
9. Harnessing macrophage signaling pathways and scalable engineering for next-generation immunotherapies.
Authors: Paasch D, Haake K, Kan C, et al.
Journal: Signal transduction and targeted therapy, 2026 Aug 18
PMID: 42608394
DOI: 10.1038/s41392-026-02907-x
Authors: Dunne F, Newman C, Alvarez-Iglesias A, et al.
Journal: JAMA, 2023 Oct 24
PMID: 37786390
DOI: 10.1001/jama.2023.19869
2. Atypical antipsychotics for autism spectrum disorder: a network meta-analysis.
Authors: Meza N, Franco JV, Sguassero Y, et al.
Journal: The Cochrane database of systematic reviews, 2025 May 21
PMID: 40396498
DOI: 10.1002/14651858.CD014965.pub2
3. A systematic review and meta-analysis of the associations between motor milestone timing and motor development in neurodevelopmental conditions.
Authors: Bowler A, Arichi T, Austerberry C, et al.
Journal: Neuroscience and biobehavioral reviews, 2024 Dec
PMID: 39067834
DOI: 10.1016/j.neubiorev.2024.105825
4. Early Metformin in Gestational Diabetes: A Randomized Clinical Trial.
Authors: Dunne F, Newman C, Alvarez-Iglesias A, et al.
Journal: JAMA, 2023 Oct 24
PMID: 37786390
DOI: 10.1001/jama.2023.19869
5. Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants: The PDA Randomized Clinical Trial.
Authors: Laughon MM, Thomas SM, Watterberg KL, et al.
Journal: JAMA, 2026 Feb 17
PMID: 41364689
DOI: 10.1001/jama.2025.23330
6. Multisystem Inflammatory Syndrome in Children (MIS-C).
Authors: Patel JM
Journal: Current allergy and asthma reports, 2022 May
PMID: 35314921
DOI: 10.1007/s11882-022-01031-4
7. Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.
Authors: Armstrong PW, Pieske B, Anstrom KJ, et al.
Journal: The New England journal of medicine, 2020 May 14
PMID: 32222134
DOI: 10.1056/NEJMoa1915928
8. Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants: The PDA Randomized Clinical Trial.
Authors: Laughon MM, Thomas SM, Watterberg KL, et al.
Journal: JAMA, 2026 Feb 17
PMID: 41364689
DOI: 10.1001/jama.2025.23330
9. Harnessing macrophage signaling pathways and scalable engineering for next-generation immunotherapies.
Authors: Paasch D, Haake K, Kan C, et al.
Journal: Signal transduction and targeted therapy, 2026 Aug 18
PMID: 42608394
DOI: 10.1038/s41392-026-02907-x
