Pediatric Frontiers: Weekly Insights
Pediatria
Pediatrics Insights: Antibiotic Stewardship, Obesity Prevention, and Heart Failure Management
This week we discuss groundbreaking pediatric research including shorter antibiotic courses for pneumonia, digital obesity prevention tools, heart failure management options, and PICU ventilation protocols.
Bibliography
1. Short-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia: The SAFER Randomized Clinical Trial.
Authors: Pernica JM, Harman S, Kam AJ, et al.
Journal: JAMA pediatrics
PMID: 33683325
DOI: 10.1001/jamapediatrics.2020.6735
2. A Digital Health Behavior Intervention to Prevent Childhood Obesity: The Greenlight Plus Randomized Clinical Trial.
Authors: Heerman WJ, Rothman RL, Sanders LM, et al.
Journal: JAMA
PMID: 39489149
DOI: 10.1001/jama.2024.22362
3. Sacubitril/Valsartan in Pediatric Heart Failure (PANORAMA-HF): A Randomized, Multicenter, Double-Blind Trial.
Authors: Shaddy R, Burch M, Kantor PF, et al.
Journal: Circulation
PMID: 39319469
DOI: 10.1161/CIRCULATIONAHA.123.066605
4. Ruxolitinib for pediatric patients with treatment-naïve and steroid-refractory acute graft-versus-host disease: the REACH4 study.
Authors: Locatelli F, Kang HJ, Bruno B, et al.
Journal: Blood
PMID: 39046767
DOI: 10.1182/blood.2023022565
5. Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units: A Randomized Clinical Trial.
Authors: Blackwood B, Tume LN, Morris KP, et al.
Journal: JAMA
PMID: 34342620
DOI: 10.1001/jama.2021.10296
Authors: Pernica JM, Harman S, Kam AJ, et al.
Journal: JAMA pediatrics
PMID: 33683325
DOI: 10.1001/jamapediatrics.2020.6735
2. A Digital Health Behavior Intervention to Prevent Childhood Obesity: The Greenlight Plus Randomized Clinical Trial.
Authors: Heerman WJ, Rothman RL, Sanders LM, et al.
Journal: JAMA
PMID: 39489149
DOI: 10.1001/jama.2024.22362
3. Sacubitril/Valsartan in Pediatric Heart Failure (PANORAMA-HF): A Randomized, Multicenter, Double-Blind Trial.
Authors: Shaddy R, Burch M, Kantor PF, et al.
Journal: Circulation
PMID: 39319469
DOI: 10.1161/CIRCULATIONAHA.123.066605
4. Ruxolitinib for pediatric patients with treatment-naïve and steroid-refractory acute graft-versus-host disease: the REACH4 study.
Authors: Locatelli F, Kang HJ, Bruno B, et al.
Journal: Blood
PMID: 39046767
DOI: 10.1182/blood.2023022565
5. Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units: A Randomized Clinical Trial.
Authors: Blackwood B, Tume LN, Morris KP, et al.
Journal: JAMA
PMID: 34342620
DOI: 10.1001/jama.2021.10296
