Inside Nephrology: A Weekly Review
Nefrologia
Advances in Nephrology and Beyond: From CKD Management to Post-COVID Microvascular Changes
This week we cover groundbreaking research in nephrology and beyond, from combination therapy for CKD to post-COVID microvascular changes and XLH growth outcomes. Join us as we discuss these important clinical advances with expert analysis.
Bibliography
1. Safety and Synergy of Finerenone and Empagliflozin in Lowering Blood Pressure.
Authors: Agarwal R, Correa-Rotter R, Navaneethan SD, et al.
Journal: Hypertension (Dallas, Tex. : 1979), 2026 Sep
PMID: 42244376
DOI: 10.1161/HYPERTENSIONAHA.126.27036
2. Natural History of C3 Glomerulopathy and Immune Complex-Associated Membranoproliferative Glomerulonephritis in Children.
Authors: Dixon BP, Laskin BL, Goodwin Davies AJ, et al.
Journal: Clinical journal of the American Society of Nephrology : CJASN, 2026 Sep 1
PMID: 42329702
DOI: 10.2215/CJN.0000001118
3. Anthropometric characteristics at birth and growth outcome in patients with X-linked hypophosphatemia treated with oral phosphate and active vitamin D.
Authors: Przygodda S, Brieger LC, Bohlen AV, et al.
Journal: Pediatric nephrology (Berlin, Germany), 2026 Sep
PMID: 41963716
DOI: 10.1007/s00467-026-07271-0
4. Low-Dose Fisetin Supplementation and Its Association With Chronic Inflammation in Middle-Aged and Older Adults: Study Protocol for a Triple-Blind, Randomised, Placebo-Controlled Trial.
Authors: Tavenier J, Berglind M, Hach LF, et al.
Journal: Basic & clinical pharmacology & toxicology, 2026 Sep
PMID: 42633989
DOI: 10.1111/bcpt.70290
5. A randomized controlled trial comparing en-bloc vs lobe-by-lobe HoLEP: surgical efficiency and early continence outcomes.
Authors: Elmorsy YH, Elshal AM, El-Nahas AR, et al.
Journal: Prostate cancer and prostatic diseases, 2026 Sep
PMID: 41198920
DOI: 10.1038/s41391-025-01040-0
6. Early predictors of MR4.5 attainment and eligibility for TKI discontinuation in CML treated with second-generation TKIs.
Authors: Ono T, Okada T, Takahashi N, et al.
Journal: Blood advances, 2026 Aug 25
PMID: 42275565
DOI: 10.1182/bloodadvances.2026019701
7. Sustained improvement in renal function with palopegteriparatide in adults with chronic hypoparathyroidism: 2-year results from the phase 3 PaTHway-trial.
Authors: Rejnmark L, Gosmanova EO, Khan AA, et al.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2026 Aug 21
PMID: 42166177
DOI: 10.1093/jbmr/zjag085
8. European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) steatotic liver disease special interest group position paper on screening, diagnosis and investigation of paediatric metabolic dysfunction-associated steatotic liver disease.
Authors: Mann JP, Lefere S, Buytaert M, et al.
Journal: Journal of pediatric gastroenterology and nutrition, 2026 Sep
PMID: 42374900
DOI: 10.1002/jpn3.70490
9. Microvascular remodeling and endothelial dysfunction across the post-COVID-19 spectrum: a prospective observational case-control study.
Authors: Wallraven T, Günthner R, Lethen I, et al.
Journal: BMC medicine, 2026 Aug 19
PMID: 42625188
DOI: 10.1186/s12916-026-05144-9
10. Upadacitinib monotherapy versus methotrexate monotherapy in methotrexate-naïve Japanese patients with rheumatoid arthritis: Long-term efficacy and safety through 5 years in the SELECT-EARLY study.
Authors: Takeuchi T, van Vollenhoven R, Ueki Y, et al.
Journal: Modern rheumatology, 2026 Aug 31
PMID: 41967478
DOI: 10.1093/mr/roag031
Authors: Agarwal R, Correa-Rotter R, Navaneethan SD, et al.
Journal: Hypertension (Dallas, Tex. : 1979), 2026 Sep
PMID: 42244376
DOI: 10.1161/HYPERTENSIONAHA.126.27036
2. Natural History of C3 Glomerulopathy and Immune Complex-Associated Membranoproliferative Glomerulonephritis in Children.
Authors: Dixon BP, Laskin BL, Goodwin Davies AJ, et al.
Journal: Clinical journal of the American Society of Nephrology : CJASN, 2026 Sep 1
PMID: 42329702
DOI: 10.2215/CJN.0000001118
3. Anthropometric characteristics at birth and growth outcome in patients with X-linked hypophosphatemia treated with oral phosphate and active vitamin D.
Authors: Przygodda S, Brieger LC, Bohlen AV, et al.
Journal: Pediatric nephrology (Berlin, Germany), 2026 Sep
PMID: 41963716
DOI: 10.1007/s00467-026-07271-0
4. Low-Dose Fisetin Supplementation and Its Association With Chronic Inflammation in Middle-Aged and Older Adults: Study Protocol for a Triple-Blind, Randomised, Placebo-Controlled Trial.
Authors: Tavenier J, Berglind M, Hach LF, et al.
Journal: Basic & clinical pharmacology & toxicology, 2026 Sep
PMID: 42633989
DOI: 10.1111/bcpt.70290
5. A randomized controlled trial comparing en-bloc vs lobe-by-lobe HoLEP: surgical efficiency and early continence outcomes.
Authors: Elmorsy YH, Elshal AM, El-Nahas AR, et al.
Journal: Prostate cancer and prostatic diseases, 2026 Sep
PMID: 41198920
DOI: 10.1038/s41391-025-01040-0
6. Early predictors of MR4.5 attainment and eligibility for TKI discontinuation in CML treated with second-generation TKIs.
Authors: Ono T, Okada T, Takahashi N, et al.
Journal: Blood advances, 2026 Aug 25
PMID: 42275565
DOI: 10.1182/bloodadvances.2026019701
7. Sustained improvement in renal function with palopegteriparatide in adults with chronic hypoparathyroidism: 2-year results from the phase 3 PaTHway-trial.
Authors: Rejnmark L, Gosmanova EO, Khan AA, et al.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2026 Aug 21
PMID: 42166177
DOI: 10.1093/jbmr/zjag085
8. European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) steatotic liver disease special interest group position paper on screening, diagnosis and investigation of paediatric metabolic dysfunction-associated steatotic liver disease.
Authors: Mann JP, Lefere S, Buytaert M, et al.
Journal: Journal of pediatric gastroenterology and nutrition, 2026 Sep
PMID: 42374900
DOI: 10.1002/jpn3.70490
9. Microvascular remodeling and endothelial dysfunction across the post-COVID-19 spectrum: a prospective observational case-control study.
Authors: Wallraven T, Günthner R, Lethen I, et al.
Journal: BMC medicine, 2026 Aug 19
PMID: 42625188
DOI: 10.1186/s12916-026-05144-9
10. Upadacitinib monotherapy versus methotrexate monotherapy in methotrexate-naïve Japanese patients with rheumatoid arthritis: Long-term efficacy and safety through 5 years in the SELECT-EARLY study.
Authors: Takeuchi T, van Vollenhoven R, Ueki Y, et al.
Journal: Modern rheumatology, 2026 Aug 31
PMID: 41967478
DOI: 10.1093/mr/roag031
