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Nephrology Updates: From Syphilis-Associated MN to HDMTX Nephrotoxicity

Inside Nephrology: A Weekly Review

Nefrologia

Nephrology Updates: From Syphilis-Associated MN to HDMTX Nephrotoxicity

This week's nephrology update covers syphilis-associated membranous nephropathy, the global CKD burden, finerenone outcomes, HDMTX nephrotoxicity management, and innovative approaches to resistant infections and transplant diagnostics.

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Bibliografia

1. A case of membranous nephropathy during asymptomatic syphilis.
Authors: Kobayashi Y, Doke T, Hayashi M, et al.
Journal: CEN case reports, 2026 Sep 24
PMID: 42786375
DOI: 10.1007/s13730-026-01183-6


2. Management of critically ill cancer patients. Expert consensus statement of the "Intensive Care for Hematology and Oncology Patients" (iCHOP) Working Group of the German Society of Hematology and Oncology (DGHO), Austrian Society of Hematology and Oncology (OeGHO), German Society for Medical Intensive Care Medicine and Emergency Medicine (DGIIN), and Austrian Society of Medical and General Intensive Care and Emergency Medicine (ÖGIAIN).
Authors: Tzalavras A, Busch E, Böll B, et al.
Journal: European journal of cancer (Oxford, England : 1990), 2026 Sep 9
PMID: 42418966
DOI: 10.1016/j.ejca.2026.116924


3. KRAS Mutations in Duodenal Lavage Fluid After Secretin Stimulation for Detection of Pancreatic Cancer.
Authors: Yachida S, Yoshinaga S, Shiba S, et al.
Journal: Annals of surgery, 2026 Oct 1
PMID: 39902566
DOI: 10.1097/SLA.0000000000006645


4. The updated global burden of chronic kidney disease: one death every 20 seconds.
Authors: Ortiz A, Lees JS, Torra R, et al.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2026 Sep 30
PMID: 41739048
DOI: 10.1093/ndt/gfag040


5. Real-World Effectiveness and Safety of Finerenone in People With Type 2 Diabetes and Chronic Kidney Disease: A Spanish Multicentre Retrospective Observational Study (MEDFINE-RWD).
Authors: Moreno-Pérez O, Tejera-Muñoz A, Tomás-Gómez P, et al.
Journal: Diabetes, obesity & metabolism, 2026 Oct
PMID: 42533276
DOI: 10.1111/dom.71160


6. A Cerebral Ethiodized Embolism after Lymphangiography: A Case Report and Literature Review.
Authors: Sawada J, Iwamoto H, Ishitoya S, et al.
Journal: Internal medicine (Tokyo, Japan), 2026 Oct 1
PMID: 41730621
DOI: 10.2169/internalmedicine.6727-25


7. A nephrology perspective on the clinical impact and management of delayed high-dose methotrexate elimination.
Authors: Soler MJ, Cosmai L, Forni L, et al.
Journal: Expert review of anticancer therapy, 2026 Oct
PMID: 42187128
DOI: 10.1080/14737140.2026.2677940


8. Normalization of nCounter Gene Expression Data Alters Molecular Diagnostics in Kidney Transplantation.
Authors: Piedrafita A, Sablik M, Preka E, et al.
Journal: Journal of the American Society of Nephrology : JASN, 2026 Oct 1
PMID: 42024462
DOI: 10.1681/ASN.0000001107


9. Calciphylaxis complicated by NDM-1-producing Pseudomonas aeruginosa: first experience with cefepime-zidebactam alongside phage therapy in the USA.
Authors: Ulloa ER, Jaffurs D, Tran MT, et al.
Journal: The Lancet. Infectious diseases, 2026 Oct
PMID: 42263718
DOI: 10.1016/S1473-3099(26)00176-3


10. Anti-obesity medications in adults with congenital heart disease: a comprehensive review and expert clinical recommendations.
Authors: Mitropoulou P, Prokšelj K, Janež A, et al.
Journal: European heart journal. Quality of care & clinical outcomes, 2026 Sep 16
PMID: 41992443
DOI: 10.1093/ehjqcco/qcag067

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