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Inside Nephrology: A Weekly Review
Nefrologia
Precision Medicine in Prediabetes and Kidney Disease
This episode explores advances in precision medicine for prediabetes and kidney disease, covering subtype-specific interventions, novel therapies for resistant hypertension, the gut-kidney axis, and implementation challenges for clinical guidelines.
Bibliography
1. Beyond Glucose-Rethinking Prediabetes for Precision Prevention.
Authors: Wagner R, Selvin E, Sehgal R, et al.
Journal: Diabetes care, 2026 Feb 1
PMID: 40932411
DOI: 10.2337/dci25-0054
2. Complement-targeting therapies in hemolytic diseases.
Authors: Duval A, Roquigny J, Frémeaux-Bacchi V
Journal: Current opinion in immunology, 2026 Feb
PMID: 41166773
DOI: 10.1016/j.coi.2025.102686
3. Molecular pathways of kidney development and their applications to clinical research.
Authors: Ehrhart F, Martens H, Rosenblum ND, et al.
Journal: Kidney international, 2026 Feb
PMID: 41271103
DOI: 10.1016/j.kint.2025.09.032
4. Vasculopathy and vasculitis associated with levamisole-adulterated cocaine: a systematic review.
Authors: Scoglio M, Orlando C, Milani GP, et al.
Journal: Journal of autoimmunity, 2026 Feb
PMID: 41330036
DOI: 10.1016/j.jaut.2025.103505
5. From global guidelines for cardio-kidney-metabolic diseases management to national implementation: perspectives from the guideline workshop taskforce.
Authors: Wanner C, Cosentino F, Barnard-Kelly K, et al.
Journal: Cardiovascular diabetology, 2026 Feb 23
PMID: 41731496
DOI: 10.1186/s12933-026-03098-z
6. Aprocitentan in Patients With Chronic Kidney Disease and Resistant Hypertension.
Authors: Rossignol P, Clozel M, Dreier RF, et al.
Journal: Hypertension (Dallas, Tex. : 1979), 2026 Feb
PMID: 41363010
DOI: 10.1161/HYPERTENSIONAHA.125.25563
7. Longitudinal multiomic signatures of ARDS and sepsis inflammatory phenotypes identify pathways associated with mortality.
Authors: Alipanah-Lechner N, Neyton L, Sinha P, et al.
Journal: The Journal of clinical investigation, 2026 Feb 2
PMID: 41329523
DOI: 10.1172/JCI196290
8. Clinical practice guidelines for the management of differences of sex development in Japan.
Authors: Ishii T, Kashimada K, Kawai M, et al.
Journal: Endocrine journal, 2026 Feb 2
PMID: 41338999
DOI: 10.1507/endocrj.EJ25-0392
9. From discoveries in ageing research to therapeutics for healthy ageing.
Authors: Campisi J, Kapahi P, Lithgow GJ, et al.
Journal: Nature, 2019 Jul
PMID: 31292558
DOI: 10.1038/s41586-019-1365-2
10. Pediatric and adult point of view on the gut-kidney axis in CKD.
Authors: Holle J, Behrens F, Koppe L
Journal: Pediatric nephrology (Berlin, Germany), 2026 Mar
PMID: 40622577
DOI: 10.1007/s00467-025-06780-8
Authors: Wagner R, Selvin E, Sehgal R, et al.
Journal: Diabetes care, 2026 Feb 1
PMID: 40932411
DOI: 10.2337/dci25-0054
2. Complement-targeting therapies in hemolytic diseases.
Authors: Duval A, Roquigny J, Frémeaux-Bacchi V
Journal: Current opinion in immunology, 2026 Feb
PMID: 41166773
DOI: 10.1016/j.coi.2025.102686
3. Molecular pathways of kidney development and their applications to clinical research.
Authors: Ehrhart F, Martens H, Rosenblum ND, et al.
Journal: Kidney international, 2026 Feb
PMID: 41271103
DOI: 10.1016/j.kint.2025.09.032
4. Vasculopathy and vasculitis associated with levamisole-adulterated cocaine: a systematic review.
Authors: Scoglio M, Orlando C, Milani GP, et al.
Journal: Journal of autoimmunity, 2026 Feb
PMID: 41330036
DOI: 10.1016/j.jaut.2025.103505
5. From global guidelines for cardio-kidney-metabolic diseases management to national implementation: perspectives from the guideline workshop taskforce.
Authors: Wanner C, Cosentino F, Barnard-Kelly K, et al.
Journal: Cardiovascular diabetology, 2026 Feb 23
PMID: 41731496
DOI: 10.1186/s12933-026-03098-z
6. Aprocitentan in Patients With Chronic Kidney Disease and Resistant Hypertension.
Authors: Rossignol P, Clozel M, Dreier RF, et al.
Journal: Hypertension (Dallas, Tex. : 1979), 2026 Feb
PMID: 41363010
DOI: 10.1161/HYPERTENSIONAHA.125.25563
7. Longitudinal multiomic signatures of ARDS and sepsis inflammatory phenotypes identify pathways associated with mortality.
Authors: Alipanah-Lechner N, Neyton L, Sinha P, et al.
Journal: The Journal of clinical investigation, 2026 Feb 2
PMID: 41329523
DOI: 10.1172/JCI196290
8. Clinical practice guidelines for the management of differences of sex development in Japan.
Authors: Ishii T, Kashimada K, Kawai M, et al.
Journal: Endocrine journal, 2026 Feb 2
PMID: 41338999
DOI: 10.1507/endocrj.EJ25-0392
9. From discoveries in ageing research to therapeutics for healthy ageing.
Authors: Campisi J, Kapahi P, Lithgow GJ, et al.
Journal: Nature, 2019 Jul
PMID: 31292558
DOI: 10.1038/s41586-019-1365-2
10. Pediatric and adult point of view on the gut-kidney axis in CKD.
Authors: Holle J, Behrens F, Koppe L
Journal: Pediatric nephrology (Berlin, Germany), 2026 Mar
PMID: 40622577
DOI: 10.1007/s00467-025-06780-8
