Advancements in Gynecology: A Weekly Review
Ginecologia e Ostetricia
Preterm Birth: Surprising Risk Factors and New Frontiers in Prevention
This week on Advancements in Gynecology: A Weekly Review by Medicalchannel, we uncover the latest science on preterm birth—still one of obstetrics’ biggest challenges. From hidden inflammatory markers and environmental stressors to amniotic cell research and microbiome insights, these discoveries are rewriting how we predict and prevent early delivery.
Bibliography
- Wang J et al. Preterm birth rates and risk factors in women with cervical incompetence undergoing prophylactic cerclage: systematic review & meta-analysis. J Obstet Gynaecol. 2025;45(1):2549996. doi:10.1080/01443615.2025.2549996.
- Fraison E et al. Childhood/adolescent chemotherapy and risk of preterm birth: systematic review & network meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2025;314:114665. doi:10.1016/j.ejogrb.2025.114665.
- Mayne G et al. Stress-induced developmental plasticity and spontaneous preterm birth: eco-evo-devo review. Eur J Obstet Gynecol Reprod Biol X. 2025;27:100409. doi:10.1016/j.eurox.2025.100409.
- Di Renzo GC et al. Predicting and preventing preterm birth in Europe: current challenges. J Matern Fetal Neonatal Med. 2025;38(1):2547687. doi:10.1080/14767058.2025.2547687.
- Meng L et al. Amniotic epithelial cells in preterm birth: mechanisms & clinical implications. Front Cell Dev Biol. 2025;13:1590212. doi:10.3389/fcell.2025.1590212.
- Al Baloushi M et al. Amniotic fluid sludge as ultrasound marker of intra-amniotic infection and preterm birth risk. Diagnostics (Basel). 2025;15(16):2080. doi:10.3390/diagnostics15162080.
- Barry A et al. Preterm birth and malaria susceptibility in offspring of multigravid women. JAMA Netw Open. 2025;8(9):e2532179. doi:10.1001/jamanetworkopen.2025.32179.
- Raghavan S et al. Heat/air pollution exposure in pregnancy and preterm birth in LMICs: systematic review & meta-analysis. BMJ Paediatr Open. 2025;9(1):e003428. doi:10.1136/bmjpo-2025-003428.
- Erickson I et al. Host–microbiome interactions in preterm infants. Infect Immun. 2025;93(9):e0050124. doi:10.1128/iai.00501-24.
- Mol BW et al. Ebopiprant to delay preterm birth: phase 2a randomized trial. Eur J Obstet Gynecol Reprod Biol. 2025;313:114637. doi:10.1016/j.ejogrb.2025.114637.
