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Pregnancy Challenges and Breakthroughs in Gynecology

Advancements in Gynecology: A Weekly Review

Ginecologia e Ostetricia

Pregnancy Challenges and Breakthroughs in Gynecology

This week we explore remarkable cases in pregnancy after major medical interventions, debate the value of third-trimester ultrasounds, examine new breast cancer treatments, and discuss cutting-edge research in genetic conditions, recurrent pregnancy loss, and neonatal health.

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Bibliography

1. Successful Spontaneous Twin Pregnancy Following Bone Marrow Transplant and Gastric Cancer Surgery: A Case Report.
Authors: Almuhaisen HKS, AlShubat SA, AlRaqeeb AN, et al.
Journal: The American journal of case reports, 2026 Apr 12
PMID: 41967022
DOI: 10.12659/AJCR.951965


2. Third trimester ultrasound. A long-standing debate.
Authors: López Soto Á, Velasco Martínez M, Meseguer González JL, et al.
Journal: Taiwanese journal of obstetrics & gynecology, 2021 May
PMID: 33966720
DOI: 10.1016/j.tjog.2021.03.004


3. A phase III trial of adjuvant ribociclib plus endocrine therapy versus endocrine therapy alone in patients with HR-positive/HER2-negative early breast cancer: final invasive disease-free survival results from the NATALEE trial.
Authors: Hortobagyi GN, Lacko A, Sohn J, et al.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology, 2025 Feb
PMID: 39442617
DOI: 10.1016/j.annonc.2024.10.015


4. Hypertrophic Cardiomyopathy as a Key Feature of MRAS-Related Noonan Syndrome: New Case and Comprehensive Literature Review.
Authors: Martineau R, Wells C, Fuchs F, et al.
Journal: Prenatal diagnosis, 2026 Apr
PMID: 41866303
DOI: 10.1002/pd.70134


5. HLA-G and Recurrent Pregnancy Loss.
Authors: Barbaro G, Inversetti A, Cristodoro M, et al.
Journal: International journal of molecular sciences, 2023 Jan 29
PMID: 36768880
DOI: 10.3390/ijms24032557


6. Gestational diabetes, human milk oligosaccharide concentrations, and their links to infant weight gain and the gut microbiome in a United States observational cohort.
Authors: Furst AJ, Johnson KE, Nagel EM, et al.
Journal: The American journal of clinical nutrition, 2026 Apr
PMID: 41672407
DOI: 10.1016/j.ajcnut.2026.101235


7. Human papillomavirus vaccination: a case study in translational science.
Authors: Palmer AK, Harris AL, Jacobson RM
Journal: Clinical and translational science, 2014 Oct
PMID: 24841923
DOI: 10.1111/cts.12166


8. New perspectives on fetal and neonatal alloimmune thrombocytopenia for obstetricians.
Authors: Zhao Y, Liu P, Chen L, et al.
Journal: Frontiers in immunology, 2026
PMID: 41993210
DOI: 10.3389/fimmu.2026.1783176


9. Impact of prophylactic oral azithromycin during labor on Azithromycin Resistance (AMR) in nasal Staphylococcus aureus and Streptococcus pneumoniae in women and infants in the multi-country Azithromycin Prevention in Labor Use Study (A-PLUS).
Authors: Hibberd PL, Kim JH, Trotta M, et al.
Journal: PloS one, 2026
PMID: 41996390
DOI: 10.1371/journal.pone.0346174


10. Pediatrics Consequences of Caesarean Section-A Systematic Review and Meta-Analysis.
Authors: Słabuszewska-Jóźwiak A, Szymański JK, Ciebiera M, et al.
Journal: International journal of environmental research and public health, 2020 Oct 31
PMID: 33142727
DOI: 10.3390/ijerph17218031

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