Advancements in Gynecology: A Weekly Review
Ginecologia e Ostetricia
Gynecology and Obstetrics Insights: Surgical Advances and Targeted Therapies
This episode covers groundbreaking research in gynecologic oncology including surgical de-escalation for cervical cancer, targeted therapies for HER2+ breast cancer, and biomarker-driven approaches in endometrial cancer treatment.
Bibliography
1. Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial.
Authors: Walsh TS, Parker RA, Aitken LM, et al.
Journal: JAMA
PMID: 40388916
DOI: 10.1001/jama.2025.7200
2. Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.
Authors: Oki R, Izumi Y, Fujita K, et al.
Journal: JAMA neurology
PMID: 35532908
DOI: 10.1001/jamaneurol.2022.0901
3. Effect of Physical Therapy vs Arthroscopic Partial Meniscectomy in People With Degenerative Meniscal Tears: Five-Year Follow-up of the ESCAPE Randomized Clinical Trial.
Authors: Noorduyn JCA, van de Graaf VA, Willigenburg NW, et al.
Journal: JAMA network open
PMID: 35802374
DOI: 10.1001/jamanetworkopen.2022.20394
4. Oral versus Intravenous Antibiotics for Bone and Joint Infection.
Authors: Li HK, Rombach I, Zambellas R, et al.
Journal: The New England journal of medicine
PMID: 30699315
DOI: 10.1056/NEJMoa1710926
5. Phase 2b randomized clinical trial of amlitelimab, an anti-OX40 ligand antibody, in patients with moderate-to-severe atopic dermatitis.
Authors: Weidinger S, Blauvelt A, Papp KA, et al.
Journal: The Journal of allergy and clinical immunology
PMID: 39522654
DOI: 10.1016/j.jaci.2024.10.031
Authors: Walsh TS, Parker RA, Aitken LM, et al.
Journal: JAMA
PMID: 40388916
DOI: 10.1001/jama.2025.7200
2. Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.
Authors: Oki R, Izumi Y, Fujita K, et al.
Journal: JAMA neurology
PMID: 35532908
DOI: 10.1001/jamaneurol.2022.0901
3. Effect of Physical Therapy vs Arthroscopic Partial Meniscectomy in People With Degenerative Meniscal Tears: Five-Year Follow-up of the ESCAPE Randomized Clinical Trial.
Authors: Noorduyn JCA, van de Graaf VA, Willigenburg NW, et al.
Journal: JAMA network open
PMID: 35802374
DOI: 10.1001/jamanetworkopen.2022.20394
4. Oral versus Intravenous Antibiotics for Bone and Joint Infection.
Authors: Li HK, Rombach I, Zambellas R, et al.
Journal: The New England journal of medicine
PMID: 30699315
DOI: 10.1056/NEJMoa1710926
5. Phase 2b randomized clinical trial of amlitelimab, an anti-OX40 ligand antibody, in patients with moderate-to-severe atopic dermatitis.
Authors: Weidinger S, Blauvelt A, Papp KA, et al.
Journal: The Journal of allergy and clinical immunology
PMID: 39522654
DOI: 10.1016/j.jaci.2024.10.031
