Advancements in Gynecology: A Weekly Review
Ginecologia e Ostetricia
Closing the Gap: The Global Challenge of HPV Vaccination and Cancer Prevention
HPV vaccination rates are falling short of global targets, threatening progress in cancer prevention. This episode examines the latest research on vaccine uptake, global disparities, and emerging strategies to boost immunization — from pay-it-forward models to next-generation therapeutic vaccines.
Bibliography
- Regmi NP et al. Tdap, MenACWY, HPV, seasonal influenza, and COVID-19 vaccination status among US teens aged 13–17 years in 2022. BMC Public Health. 2025;25(1):3094. doi:10.1186/s12889-025-24434-0.
- Ozdogan M et al. Molecular insights into HPV-driven head and neck cancers: from viral oncoproteins to precision therapeutics. Viruses. 2025;17(9):1276. doi:10.3390/v17091276.
- Sun J et al. HPV vaccination willingness and influencing factors among women in China: a systematic review and meta-analysis. Prev Med Rep. 2025;58:103215. doi:10.1016/j.pmedr.2025.103215.
- Lo SHS et al. Effects of an educational intervention to improve HPV vaccination acceptance and uptake among adolescent girls: a cluster RCT. BMC Public Health. 2025;25(1):3419. doi:10.1186/s12889-025-24511-4.
- Chen G et al. Global burden and risk factors of female cancers in child-bearing age: a GBD-based analysis and projection to 2030. Transl Oncol. 2025;60:102473. doi:10.1016/j.tranon.2025.102473.
- Chen Q et al. Temporal changes in HPV prevalence and distribution in mainland China: analysis of 1.07 million females (2010–2021). BMC Public Health. 2025;25(1):3083. doi:10.1186/s12889-025-24323-6.
- Wongkalasin N et al. Global estimates of HPV-related noncervical cancer burden in people with HIV and AIDS: a systematic review and modeling study. Open Forum Infect Dis. 2025;12(10):ofaf577. doi:10.1093/ofid/ofaf577.
- Barker HE et al. Genomics of cervical, vulvar, and vaginal cancers and the potential of precision medicine. Ther Adv Med Oncol. 2025;17:17588359251363499. doi:10.1177/17588359251363499.
- Middeldorp M et al. Quadrivalent HPV Vaccine Evaluation Study with addition of the Nonavalent Vaccine (QUEST-ADVANCE): study protocol. BMJ Open. 2025;15(9):e100560. doi:10.1136/bmjopen-2025-100560.
- Lu Y et al. Causal mediation analysis of a pay-it-forward strategy to increase HPV vaccine uptake in China. BMJ Open. 2025;15(9):e095248. doi:10.1136/bmjopen-2024-095248.
