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Advancements in Gastroenterology: A Weekly Review

Gastroenterologia

Revolutionizing Gastrointestinal Treatment: New Insights Unveiled

In this episode we explore recent groundbreaking studies challenging traditional treatment paradigms. Highlights include a complex pediatric case of gastrointestinal stromal tumors requiring nuanced surgical intervention, novel insights into glucose-dependent insulinotropic polypeptide (GIP) roles beyond metabolism, and critical evaluations of research methodologies in clinical trials and gastrointestinal assessments. We also discuss promising developments in probiotics for precancerous lesions, FGFR-targeted therapies in gastrointestinal cancers, and the long-term gastrointestinal effects of COVID-19. Finally, we review advances in integrated genomic approaches for personalized cancer treatment. This episode underscores the urgent need for standardized research protocols and integrated strategies to advance patient care in gastroenterology.

Bibliography

– Israel SD, Del Cañizo A, Monje S, et al. Gastrointestinal stromal tumor surgery in pediatrics. Cir Pediatr. 2025 Apr 7;38(2):74–76. doi: 10.54847/cp.2025.02.17. PMID: 40196883.

– Müller TD, Adriaenssens A, Ahrén B, et al. Glucose-dependent insulinotropic polypeptide (GIP). Mol Metab. 2025 May;95:102118. doi: 10.1016/j.molmet.2025.102118. PMID: 40024571; PMCID: PMC11931254.

– Fan X, Wang Y, Cao J, et al. Clinical study status of diabetic gastrointestinal diseases. Front Endocrinol (Lausanne). 2025 Apr 9;16:1568552. doi: 10.3389/fendo.2025.1568552. PMID: 40270718; PMCID: PMC12014455.

– Soliman OM, Mikocka-Walus A, Warner MM, et al. Systematic Review and Meta-Analysis: Examining the Psychometric Evaluations of Disordered Eating Scales in Adults Living With Gastrointestinal Conditions. Neurogastroenterol Motil. 2025 May;37(5):e15018. doi: 10.1111/nmo.15018. PMID: 39928514; PMCID: PMC11996053.

– Huang Z, Zhu J, Bu X, et al. Probiotics and prebiotics: new treatment strategies for oral potentially malignant disorders and gastrointestinal precancerous lesions. NPJ Biofilms Microbiomes. 2025 Apr 8;11(1):55. doi: 10.1038/s41522-025-00688-9. PMID: 40199865; PMCID: PMC11978799.

– Seraji N, Berger I. FGFR as a Predictive Marker for Targeted Therapy in Gastrointestinal Malignancies: A Systematic Review. J Gastrointest Cancer. 2025 Apr 9;56(1):96. doi: 10.1007/s12029-025-01214-y. PMID: 40205008; PMCID: PMC11982104.

– Chung J, Pierce J, Franklin C, et al. Translating animal models of SARS-CoV-2 infection to vascular, neurological and gastrointestinal manifestations of COVID-19. Dis Model Mech. 2025 Sep 1;18(9):dmm052086. doi: 10.1242/dmm.052086. PMID: 40195851; PMCID: PMC12010913.

– Reyila A, Gao X, Yu J, Nie Y. Insight into the role of DNA methylation in prognosis and treatment response prediction of gastrointestinal cancers. Epigenomics. 2025 May;17(7):475–488. doi: 10.1080/17501911.2025.2476380. PMID: 40084815; PMCID: PMC12026041.

– Asmat-Abanto AS, Portocarrero-Reyes A, Espejo-Carrera RE, et al. Bibliometric analysis in Scopus of scientific production on the relationship between periodontitis and gastrointestinal cancer (2014–2023). Med Oral Patol Oral Cir Bucal. 2025 May 1;30(3):e422–e430. doi: 10.4317/medoral.26969. PMID: 39864084; PMCID: PMC12019650.

– Li YR, Wang G, He WT, Liu T. Application of aggregation-induced emission materials in gastrointestinal diseases. World J Gastroenterol. 2025 Apr 28;31(16):105378. doi: 10.3748/wjg.v31.i16.105378. PMID: 40308804; PMCID: PMC12038521.

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