Advancements in Gastroenterology: A Weekly Review
Gastroenterologia
Gastroenterology Breakthroughs: From Gut Motility to Microbiota
This week we explore groundbreaking gastroenterology research, from genetic influences on gut motility to innovative approaches for liver metastases and microbiota-based therapies. Our experts discuss key clinical guidelines and diagnostic advances shaping modern GI practice.
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Bibliografia
1. Genetic dissection of stool frequency implicates vitamin B1 metabolism and other actionable pathways in the modulation of gut motility.
Authors: Díaz-Muñoz C, Bozzarelli I, Lopera-Maya EA, et al.
Journal: Gut
PMID: 41558814
DOI: 10.1136/gutjnl-2025-337059
2. Residual lipid risk in atherosclerotic cardiovascular disease.
Authors: Nordestgaard BG, Hegele RA
Journal: European heart journal
PMID: 41701506
DOI: 10.1093/eurheartj/ehag087
3. Asian Pacific Association of Gastroenterology (APAGE) Clinical Practice Guidelines on the Use of Small Molecules and IL-23 p19 Inhibitors in Ulcerative Colitis and Crohn's Disease.
Authors: Ooi CJ, Ling KL, Limsrivilai J, et al.
Journal: Journal of gastroenterology and hepatology
PMID: 42117726
DOI: 10.1111/jgh.70379
4. Intraperitoneal and Intravenous Paclitaxel Plus S-1 for Gastric Cancer With Peritoneal Metastasis: A Phase 3 Randomized Clinical Trial.
Authors: Yan C, Yang Z, Shi Z, et al.
Journal: JAMA oncology
PMID: 42166134
DOI: 10.1001/jamaoncol.2026.1347
5. Associations between demographic, clinical and dietary factors and flares in inflammatory bowel disease: the PRognostic effect of Environmental factors in Crohn's and Colitis (PREdiCCt) prospective cohort study.
Authors: Constantine-Cooke N, Gros B, Plevris N, et al.
Journal: Gut
PMID: 41554630
DOI: 10.1136/gutjnl-2025-337846
6. Clinical Trial Endpoints for Perianal Fistulizing Crohn's Disease.
Authors: Reinisch W, Atreya R, Rieder F, et al.
Journal: The American journal of gastroenterology
PMID: 41504318
DOI: 10.14309/ajg.0000000000003906
7. Colorectal cancer liver metastases: mechanism and therapy.
Authors: Liu S, Ban L, Zhang W, et al.
Journal: Frontiers in immunology
PMID: 42500682
DOI: 10.3389/fimmu.2026.1861130
8. Gut microbiota in health and disease.
Authors: Li Y, Xiao X, Jiang X, et al.
Journal: Molecular biomedicine
PMID: 42474869
DOI: 10.1186/s43556-026-00512-6
9. Budd-Chiari Syndrome: Presentation, Management, and Prognosis.
Authors: Amjad W, Thuluvath PJ
Journal: The American journal of gastroenterology
PMID: 41384820
DOI: 10.14309/ajg.0000000000003886
10. Performance Evaluation of the Xpert® HCV Test on Fingerstick Blood in a Prospective Observational Clinical Study at CLIA-Waived Sites in the United States.
Authors: Havens JR, Fluker SA, Schimmel J, et al.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
PMID: 41823658
DOI: 10.1093/cid/ciag173
Authors: Díaz-Muñoz C, Bozzarelli I, Lopera-Maya EA, et al.
Journal: Gut
PMID: 41558814
DOI: 10.1136/gutjnl-2025-337059
2. Residual lipid risk in atherosclerotic cardiovascular disease.
Authors: Nordestgaard BG, Hegele RA
Journal: European heart journal
PMID: 41701506
DOI: 10.1093/eurheartj/ehag087
3. Asian Pacific Association of Gastroenterology (APAGE) Clinical Practice Guidelines on the Use of Small Molecules and IL-23 p19 Inhibitors in Ulcerative Colitis and Crohn's Disease.
Authors: Ooi CJ, Ling KL, Limsrivilai J, et al.
Journal: Journal of gastroenterology and hepatology
PMID: 42117726
DOI: 10.1111/jgh.70379
4. Intraperitoneal and Intravenous Paclitaxel Plus S-1 for Gastric Cancer With Peritoneal Metastasis: A Phase 3 Randomized Clinical Trial.
Authors: Yan C, Yang Z, Shi Z, et al.
Journal: JAMA oncology
PMID: 42166134
DOI: 10.1001/jamaoncol.2026.1347
5. Associations between demographic, clinical and dietary factors and flares in inflammatory bowel disease: the PRognostic effect of Environmental factors in Crohn's and Colitis (PREdiCCt) prospective cohort study.
Authors: Constantine-Cooke N, Gros B, Plevris N, et al.
Journal: Gut
PMID: 41554630
DOI: 10.1136/gutjnl-2025-337846
6. Clinical Trial Endpoints for Perianal Fistulizing Crohn's Disease.
Authors: Reinisch W, Atreya R, Rieder F, et al.
Journal: The American journal of gastroenterology
PMID: 41504318
DOI: 10.14309/ajg.0000000000003906
7. Colorectal cancer liver metastases: mechanism and therapy.
Authors: Liu S, Ban L, Zhang W, et al.
Journal: Frontiers in immunology
PMID: 42500682
DOI: 10.3389/fimmu.2026.1861130
8. Gut microbiota in health and disease.
Authors: Li Y, Xiao X, Jiang X, et al.
Journal: Molecular biomedicine
PMID: 42474869
DOI: 10.1186/s43556-026-00512-6
9. Budd-Chiari Syndrome: Presentation, Management, and Prognosis.
Authors: Amjad W, Thuluvath PJ
Journal: The American journal of gastroenterology
PMID: 41384820
DOI: 10.14309/ajg.0000000000003886
10. Performance Evaluation of the Xpert® HCV Test on Fingerstick Blood in a Prospective Observational Clinical Study at CLIA-Waived Sites in the United States.
Authors: Havens JR, Fluker SA, Schimmel J, et al.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
PMID: 41823658
DOI: 10.1093/cid/ciag173
