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Innovations in Gastroenterology and Hepatology

Advancements in Gastroenterology: A Weekly Review

Gastroenterologia

Innovations in Gastroenterology and Hepatology

This week's episode covers groundbreaking research in gastroenterology and hepatology, including regional differences in ulcerative colitis outcomes, innovative pancreatic cancer detection methods, and novel approaches to liver disease management.

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Bibliografia

1. Mitochondrial dysfunction as a metabolic checkpoint of immunotherapy response in colorectal cancer.
Authors: Tomassini L, Colella M, Monteleone G, et al.
Journal: Frontiers in immunology, 2026
PMID: 42835854
DOI: 10.3389/fimmu.2026.1908222


2. Distinct predictive factors for acute severe ulcerative colitis in East Asian and Western populations.
Authors: Kim ES, Kim DH, Kim SJ, et al.
Journal: Inflammatory bowel diseases, 2026 Oct 1
PMID: 42247237
DOI: 10.1093/ibd/izag098


3. Ferroptosis in liver biology and diseases.
Authors: Cao P, He P, Du K, et al.
Journal: Hepatology communications, 2026 Oct 1
PMID: 42809682
DOI: 10.1097/HC9.0000000000001058


4. Overcoming Biophysical Barriers in Melanoma Photomedicine: From Photodynamic Therapy to Smart Nanodelivery and Photoimmunotherapy.
Authors: Russano F, Dall'Olmo L, Brugnolo D, et al.
Journal: International journal of molecular sciences, 2026 Sep 13
PMID: 42794589
DOI: 10.3390/ijms27188156


5. KRAS Mutations in Duodenal Lavage Fluid After Secretin Stimulation for Detection of Pancreatic Cancer.
Authors: Yachida S, Yoshinaga S, Shiba S, et al.
Journal: Annals of surgery, 2026 Oct 1
PMID: 39902566
DOI: 10.1097/SLA.0000000000006645


6. Evolving Concepts of Treatment Targets for Primary Biliary Cholangitis: A Global Perspective.
Authors: Bowlus CL, Bittencourt PL, Bobat B, et al.
Journal: The American journal of gastroenterology, 2026 Oct 1
PMID: 42148535
DOI: 10.14309/ajg.0000000000004054


7. Post-translational modification crosstalk in acute pancreatitis: linking acinar stress to innate immune amplification and tissue repair.
Authors: Chen M, An P, Jing S, et al.
Journal: Frontiers in immunology, 2026
PMID: 42820106
DOI: 10.3389/fimmu.2026.1935553


8. Randomized Sham-Controlled Trial of Translumbosacral Neuromodulation Therapy for Fecal Incontinence.
Authors: Rao SSC, Yan Y, Hamdy S, et al.
Journal: Gastroenterology, 2026 Oct
PMID: 42105947
DOI: 10.1053/j.gastro.2026.04.027


9. A Cerebral Ethiodized Embolism after Lymphangiography: A Case Report and Literature Review.
Authors: Sawada J, Iwamoto H, Ishitoya S, et al.
Journal: Internal medicine (Tokyo, Japan), 2026 Oct 1
PMID: 41730621
DOI: 10.2169/internalmedicine.6727-25


10. An Effective Case of Radiofrequency Ablation with the Combination of Durvalumab and Tremelimumab Treatment for Hepatocellular Carcinoma.
Authors: Rinka K, Kioka K, Shioji R, et al.
Journal: Internal medicine (Tokyo, Japan), 2026 Oct 1
PMID: 41730620
DOI: 10.2169/internalmedicine.6699-25

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