Advancements in Gastroenterology: A Weekly Review
Gastroenterologia
Recent Advances in Gastroenterology and Hepatology
This week's episode covers groundbreaking research in gastroenterology and hepatology, including dietary management of IBS, HCC treatment advances, JAK inhibitor comparisons, MASLD-cancer associations, and innovative AI applications in endoscopy.
Bibliography
1. Efficacy of a low FODMAP diet in irritable bowel syndrome: systematic review and network meta-analysis.
Authors: Black CJ, Staudacher HM, Ford AC
Journal: Gut, 2022 Jun
PMID: 34376515
DOI: 10.1136/gutjnl-2021-325214
2. Asian Pacific Association of Gastroenterology task force recommendations on surveillance for Helicobacter pylori associated gastric premalignant conditions.
Authors: Leung WK, Ang TL, Shah S, et al.
Journal: Gut, 2026 Mar 6
PMID: 41057234
DOI: 10.1136/gutjnl-2025-335823
3. Immune-mediated adverse events and overall survival with tremelimumab plus durvalumab and durvalumab monotherapy in unresectable HCC: HIMALAYA phase III randomized clinical trial.
Authors: Lau G, Sangro B, Cheng AL, et al.
Journal: Hepatology (Baltimore, Md.), 2026 Mar 1
PMID: 40384092
DOI: 10.1097/HEP.0000000000001385
4. Comparative Effectiveness of Tofacitinib vs Upadacitinib for the Treatment of Acute Severe Ulcerative Colitis.
Authors: Honap S, St-Pierre J, Colwill M, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Mar
PMID: 40721074
DOI: 10.1016/j.cgh.2025.07.025
5. Occurrence and prognosis of metabolic dysfunction-associated steatosis liver disease and gastrointestinal tumors: a systematic review and meta-analysis.
Authors: Duan S, Wei Y, Ding Z, et al.
Journal: PeerJ, 2026
PMID: 41769402
DOI: 10.7717/peerj.20616
6. Effect of Direct-Acting Antiviral Therapy on Glycemic Control in Patients with Chronic Hepatitis C and Type 2 Diabetes: A Systematic Review and Meta-Analysis.
Authors: Hu JH, Chang ML, Lin MS, et al.
Journal: Viruses, 2026 Feb 13
PMID: 41754582
DOI: 10.3390/v18020239
7. Deciphering molecular pathways in urological cancers: A gateway to precision therapeutics.
Authors: Hushmandi K, Farahani N, Einollahi B, et al.
Journal: Journal of advanced research, 2026 Mar
PMID: 40516913
DOI: 10.1016/j.jare.2025.06.009
8. Overcoming radioresistance in prostate cancer by targeting DNA damage repair.
Authors: Matos AC, Lima M, Miranda-Gonçalves V, et al.
Journal: Cancer letters, 2026 Feb 28
PMID: 41319862
DOI: 10.1016/j.canlet.2025.218183
9. Pediatric and adult point of view on the gut-kidney axis in CKD.
Authors: Holle J, Behrens F, Koppe L
Journal: Pediatric nephrology (Berlin, Germany), 2026 Mar
PMID: 40622577
DOI: 10.1007/s00467-025-06780-8
10. Colorectal mucosal exposure area assessment using artificial intelligence: a multicenter prospective observational study.
Authors: Li J, Huang L, Luo C, et al.
Journal: Endoscopy, 2026 Mar
PMID: 40902624
DOI: 10.1055/a-2695-1832
Authors: Black CJ, Staudacher HM, Ford AC
Journal: Gut, 2022 Jun
PMID: 34376515
DOI: 10.1136/gutjnl-2021-325214
2. Asian Pacific Association of Gastroenterology task force recommendations on surveillance for Helicobacter pylori associated gastric premalignant conditions.
Authors: Leung WK, Ang TL, Shah S, et al.
Journal: Gut, 2026 Mar 6
PMID: 41057234
DOI: 10.1136/gutjnl-2025-335823
3. Immune-mediated adverse events and overall survival with tremelimumab plus durvalumab and durvalumab monotherapy in unresectable HCC: HIMALAYA phase III randomized clinical trial.
Authors: Lau G, Sangro B, Cheng AL, et al.
Journal: Hepatology (Baltimore, Md.), 2026 Mar 1
PMID: 40384092
DOI: 10.1097/HEP.0000000000001385
4. Comparative Effectiveness of Tofacitinib vs Upadacitinib for the Treatment of Acute Severe Ulcerative Colitis.
Authors: Honap S, St-Pierre J, Colwill M, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Mar
PMID: 40721074
DOI: 10.1016/j.cgh.2025.07.025
5. Occurrence and prognosis of metabolic dysfunction-associated steatosis liver disease and gastrointestinal tumors: a systematic review and meta-analysis.
Authors: Duan S, Wei Y, Ding Z, et al.
Journal: PeerJ, 2026
PMID: 41769402
DOI: 10.7717/peerj.20616
6. Effect of Direct-Acting Antiviral Therapy on Glycemic Control in Patients with Chronic Hepatitis C and Type 2 Diabetes: A Systematic Review and Meta-Analysis.
Authors: Hu JH, Chang ML, Lin MS, et al.
Journal: Viruses, 2026 Feb 13
PMID: 41754582
DOI: 10.3390/v18020239
7. Deciphering molecular pathways in urological cancers: A gateway to precision therapeutics.
Authors: Hushmandi K, Farahani N, Einollahi B, et al.
Journal: Journal of advanced research, 2026 Mar
PMID: 40516913
DOI: 10.1016/j.jare.2025.06.009
8. Overcoming radioresistance in prostate cancer by targeting DNA damage repair.
Authors: Matos AC, Lima M, Miranda-Gonçalves V, et al.
Journal: Cancer letters, 2026 Feb 28
PMID: 41319862
DOI: 10.1016/j.canlet.2025.218183
9. Pediatric and adult point of view on the gut-kidney axis in CKD.
Authors: Holle J, Behrens F, Koppe L
Journal: Pediatric nephrology (Berlin, Germany), 2026 Mar
PMID: 40622577
DOI: 10.1007/s00467-025-06780-8
10. Colorectal mucosal exposure area assessment using artificial intelligence: a multicenter prospective observational study.
Authors: Li J, Huang L, Luo C, et al.
Journal: Endoscopy, 2026 Mar
PMID: 40902624
DOI: 10.1055/a-2695-1832
