Advancements in Gastroenterology: A Weekly Review
Gastroenterologia
Advances in Gastroenterology: From Cholestasis to Crohns Disease
This week we cover Spanish guidelines for cholestatic liver diseases, location-specific Crohn's treatments, advances in MASLD therapy, and breakthroughs in eosinophilic esophagitis management. Plus updates on portal hypertension, autoimmune pancreatitis complications, and HCV treatment.
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Bibliografia
1. Spanish clinical practice guidelines for the diagnosis and management of cholestatic liver diseases in adult and pediatric population: Joint report from AEEH and SEGHNP.
Authors: Díaz-González Á, Molera C, Gómez-Domínguez E, et al.
Journal: Gastroenterologia y hepatologia, 2026 Apr
PMID: 41232665
DOI: 10.1016/j.gastrohep.2025.502629
2. Efficacy of Advanced Therapies in Achieving Remission by Disease Location in Crohn's Disease: A Systematic Review and Meta-analysis.
Authors: Lee HH, Yuan Y, Boland BS, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40712715
DOI: 10.1016/j.cgh.2025.07.009
3. Chaperonin in health and disease.
Authors: Xu P, Ji M, Zhuang W, et al.
Journal: Molecular biomedicine, 2026 Apr 1
PMID: 41920440
DOI: 10.1186/s43556-026-00437-0
4. The diagnosis and management of portal hypertension in cirrhosis: The Gastroenterological Society of Australia consensus.
Authors: Majumdar A, Holmes J, Roberts SK, et al.
Journal: Hepatology communications, 2026 Apr 1
PMID: 41921189
DOI: 10.1097/HC9.0000000000000934
5. Intestinal Ultrasound for Monitoring Postoperative Crohn's Disease: A Review and Visual Atlas.
Authors: Gu P, Karime C, Fleshner P, et al.
Journal: Inflammatory bowel diseases, 2026 Apr 1
PMID: 41335492
DOI: 10.1093/ibd/izaf248
6. Efficacy and Safety of HSK31679 in Asian Patients With MASLD: A Randomized Controlled Trial.
Authors: Xue F, Ma W, Gao J, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40846146
DOI: 10.1016/j.cgh.2025.08.009
7. Effectiveness and Safety of Orodispersible Budesonide for Eosinophilic Esophagitis: A Multicenter Real-World Study.
Authors: Maniero D, Ghisa M, Bruschi A, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40930303
DOI: 10.1016/j.cgh.2025.08.033
8. Peripancreatic Vascular Involvement and Gastric Varices in Autoimmune Pancreatitis: A Multicenter Retrospective Study.
Authors: Juri N, Masuda A, Nakano R, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40774591
DOI: 10.1016/j.cgh.2025.06.044
9. Advances in Diagnosis and Treatment With Cholangiopancreatoscopy.
Authors: Ogura T, Trong NN, Samanta J
Journal: Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2026 Apr
PMID: 41911952
DOI: 10.1111/den.70141
10. A single-arm phase IIIb study of 8-week glecaprevir/pibrentasvir treatment in adults with acute hepatitis C.
Authors: Llibre JM, Boesecke C, Moon J, et al.
Journal: Journal of hepatology, 2026 Apr
PMID: 41297677
DOI: 10.1016/j.jhep.2025.11.009
Authors: Díaz-González Á, Molera C, Gómez-Domínguez E, et al.
Journal: Gastroenterologia y hepatologia, 2026 Apr
PMID: 41232665
DOI: 10.1016/j.gastrohep.2025.502629
2. Efficacy of Advanced Therapies in Achieving Remission by Disease Location in Crohn's Disease: A Systematic Review and Meta-analysis.
Authors: Lee HH, Yuan Y, Boland BS, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40712715
DOI: 10.1016/j.cgh.2025.07.009
3. Chaperonin in health and disease.
Authors: Xu P, Ji M, Zhuang W, et al.
Journal: Molecular biomedicine, 2026 Apr 1
PMID: 41920440
DOI: 10.1186/s43556-026-00437-0
4. The diagnosis and management of portal hypertension in cirrhosis: The Gastroenterological Society of Australia consensus.
Authors: Majumdar A, Holmes J, Roberts SK, et al.
Journal: Hepatology communications, 2026 Apr 1
PMID: 41921189
DOI: 10.1097/HC9.0000000000000934
5. Intestinal Ultrasound for Monitoring Postoperative Crohn's Disease: A Review and Visual Atlas.
Authors: Gu P, Karime C, Fleshner P, et al.
Journal: Inflammatory bowel diseases, 2026 Apr 1
PMID: 41335492
DOI: 10.1093/ibd/izaf248
6. Efficacy and Safety of HSK31679 in Asian Patients With MASLD: A Randomized Controlled Trial.
Authors: Xue F, Ma W, Gao J, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40846146
DOI: 10.1016/j.cgh.2025.08.009
7. Effectiveness and Safety of Orodispersible Budesonide for Eosinophilic Esophagitis: A Multicenter Real-World Study.
Authors: Maniero D, Ghisa M, Bruschi A, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40930303
DOI: 10.1016/j.cgh.2025.08.033
8. Peripancreatic Vascular Involvement and Gastric Varices in Autoimmune Pancreatitis: A Multicenter Retrospective Study.
Authors: Juri N, Masuda A, Nakano R, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40774591
DOI: 10.1016/j.cgh.2025.06.044
9. Advances in Diagnosis and Treatment With Cholangiopancreatoscopy.
Authors: Ogura T, Trong NN, Samanta J
Journal: Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2026 Apr
PMID: 41911952
DOI: 10.1111/den.70141
10. A single-arm phase IIIb study of 8-week glecaprevir/pibrentasvir treatment in adults with acute hepatitis C.
Authors: Llibre JM, Boesecke C, Moon J, et al.
Journal: Journal of hepatology, 2026 Apr
PMID: 41297677
DOI: 10.1016/j.jhep.2025.11.009
