testo-alternativo
Herpes Simplex Virus: Why 900 Million Cases Still Elude a Cure

Advancements in Dermatology: A Weekly Review

Dermatologia e Venerologia

Herpes Simplex Virus: Why 900 Million Cases Still Elude a Cure

Despite decades of research, herpes simplex virus (HSV) continues to pose significant diagnostic and therapeutic challenges. In this episode, we explore the global burden, the complex biology of viral latency, unexpected clinical presentations, and the latest findings that could reshape prevention and treatment strategies.

Login or Register to listen to this episode

Bibliography

Patel R et al. 2024 European guidelines for the management of genital herpes. J Eur Acad Dermatol Venereol. 2025;39(4):742–758. doi: 10.1111/jdv.20450


Johnston C et al. Vaccine value profile for herpes simplex virus. Vaccine. 2024;42(19S1):S82–S100. doi: 10.1016/j.vaccine.2024.01.044


Bai L et al. A review of HSV pathogenesis, vaccine development, and advanced applications. Mol Biomed. 2024;5(1):35. doi: 10.1186/s43556-024-00199-7


Harfouche M et al. Global incidence and prevalence of HSV and genital ulcer disease in 2020: modelling analyses. Sex Transm Infect. 2025;101(4):214–223. doi: 10.1136/sextrans-2024-056307


Cao S et al. Recent advances in alphaherpesvirus latency and reactivation. Pathogens. 2024;13(9):779. doi: 10.3390/pathogens13090779


Sørensen NK et al. Venereal diseases in Denmark. Ugeskr Laeger. 2025;187(17):V05240335. doi: 10.61409/V05240335


Herbin C et al. Atypical primary HSV-2 infection: case report. J Med Case Rep. 2024;18(1):393. doi: 10.1186/s13256-024-04721-x


Tugizov S. HIV-1 Tat and disruption of epithelial barriers promoting HSV spread. Front Immunol. 2025;16:1541532. doi: 10.3389/fimmu.2025.1541532


Avitabile E et al. Protective mechanisms of vaginal lactobacilli against viral STIs. Int J Mol Sci. 2024;25(17):9168. doi: 10.3390/ijms25179168

Comments

Please Login to leave a comment.

No comments yet. Be the first to comment!