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Dermatology Breakthroughs: Psoriasis, HS, and Beyond

Advancements in Dermatology: A Weekly Review

Dermatologia e Venerologia

Dermatology Breakthroughs: Psoriasis, HS, and Beyond

This week's episode covers groundbreaking research in psoriasis combination therapy, hidradenitis suppurativa pathogenesis, and personalized approaches for chronic dermatologic conditions.

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Bibliography

1. Update of the EuroGuiDerm evidence-based guideline for the treatment of acne-Short version.
Authors: Nast A, Al Wattar BH, Beylot Barry M, et al.
Journal: Journal of the European Academy of Dermatology and Venereology : JEADV
PMID: 41847993
DOI: 10.1111/jdv.70331


2. Ixekizumab With or Without Tirzepatide in Adults With Psoriasis and Overweight or Obesity: A Phase 3b Randomized Clinical Trial.
Authors: Lebwohl M, Blauvelt A, Kartman CE, et al.
Journal: JAMA dermatology
PMID: 42139049
DOI: 10.1001/jamadermatol.2026.1753


3. Treatment Guidance for Palmoplantar Pustulosis 2022.
Authors: Japanese Dermatological Association Palmoplantar Pustulosis Treatment Guidance Drafting Committee, Terui T, Kobayashi S, et al.
Journal: The Journal of dermatology
PMID: 42252553
DOI: 10.1111/1346-8138.70246


4. Hidradenitis suppurativa: epidemiology, diagnosis, molecular pathogenesis and therapy.
Authors: Lolli MG, Sanna L, Belli R, et al.
Journal: Molecular biomedicine
PMID: 42410203
DOI: 10.1186/s43556-026-00495-4


5. Clinical and mechanistic effects of GLP-1 receptor agonists in hidradenitis suppurativa and comorbidities.
Authors: Brogaard E, Nielsen VW, Pedersen NH, et al.
Journal: Science progress
PMID: 42389771
DOI: 10.1177/00368504261464855


6. Impact of early treatment of psoriasis on disease recurrence-Results from the STEPIn study.
Authors: Iversen L, Langley RG, Gudjonsson JE, et al.
Journal: Journal of the American Academy of Dermatology
PMID: 41881197
DOI: 10.1016/j.jaad.2026.03.050


7. Virus infections and cancers: from mechanisms to therapeutics.
Authors: Li Y, Yu W, Yun J, et al.
Journal: Molecular biomedicine
PMID: 42417944
DOI: 10.1186/s43556-026-00485-6


8. Long-Term Efficacy and Safety of Ligelizumab as Re-Treatment in Patients With Chronic Spontaneous Urticaria.
Authors: Gimenez-Arnau AM, Maurer M, Reich A, et al.
Journal: Allergy
PMID: 41358486
DOI: 10.1111/all.70181


9. Spanish Clinical Management Guideline for Hidradenitis Suppurativa. Part I: Pathogenesis, Diagnosis, and Disease Staging.
Authors: Martorell A, Alfageme Roldán F, García-Martínez FJ, et al.
Journal: Actas dermo-sifiliograficas
PMID: 41865977
DOI: 10.1016/j.ad.2026.104639


10. Biomarkers for therapeutic response and adverse outcomes in atopic dermatitis: A systematic review.
Authors: Hilger E, Chan K, Yip A, et al.
Journal: Journal of the European Academy of Dermatology and Venereology : JEADV
PMID: 41619222
DOI: 10.1111/jdv.70330

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