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Dermatology Breakthroughs: From STI Prevention to Targeted Therapies

Advancements in Dermatology: A Weekly Review

Dermatologia e Venerologia

Dermatology Breakthroughs: From STI Prevention to Targeted Therapies

This week we cover groundbreaking dermatology research including STI prevention strategies, new treatments for psoriasis and atopic dermatitis, a breakthrough in uveal melanoma therapy, and important insights into contact allergens and genetic skin disorders.

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Bibliography

1. Doxycycline Prophylaxis to Prevent Sexually Transmitted Infections in Women.
Authors: Stewart J, Oware K, Donnell D, et al.
Journal: The New England journal of medicine, 2023 Dec 21
PMID: 38118022
DOI: 10.1056/NEJMoa2304007


2. Novel insights into contact dermatitis.
Authors: Johansen JD, Bonefeld CM, Schwensen JFB, et al.
Journal: The Journal of allergy and clinical immunology, 2022 Apr
PMID: 35183605
DOI: 10.1016/j.jaci.2022.02.002


3. Unveiling the IL-17 axis: an immunometabolic bridge between psoriasis and metabolic syndrome.
Authors: Gisondi P, Fratton Z, Vighi da Rosa R, et al.
Journal: The Journal of dermatological treatment, 2026 Dec
PMID: 42223088
DOI: 10.1080/09546634.2026.2673285


4. Efficacy and Safety of Upadacitinib vs Dupilumab in Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial.
Authors: Blauvelt A, Teixeira HD, Simpson EL, et al.
Journal: JAMA dermatology, 2021 Sep 1
PMID: 34347860
DOI: 10.1001/jamadermatol.2021.3023


5. Overall Survival Benefit with Tebentafusp in Metastatic Uveal Melanoma.
Authors: Nathan P, Hassel JC, Rutkowski P, et al.
Journal: The New England journal of medicine, 2021 Sep 23
PMID: 34551229
DOI: 10.1056/NEJMoa2103485


6. Overall Survival Benefit with Tebentafusp in Metastatic Uveal Melanoma.
Authors: Nathan P, Hassel JC, Rutkowski P, et al.
Journal: The New England journal of medicine, 2021 Sep 23
PMID: 34551229
DOI: 10.1056/NEJMoa2103485


7. Trichomoniasis.
Authors: Van Gerwen OT, Opsteen SA, Graves KJ, et al.
Journal: Infectious disease clinics of North America, 2023 Jun
PMID: 37005163
DOI: 10.1016/j.idc.2023.02.001


8. A biomarker-guided therapeutic map for alopecia: in vivo evidence and clinical implications.
Authors: Nareswari A, Tamtomo DG, Kariosentono H, et al.
Journal: Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2026 Jun
PMID: 42241634


9. Genotypic and phenotypic features of 23 Egyptian patients with tuberous sclerosis complex.
Authors: Othman AA, Sadek AA, Aladawy MA, et al.
Journal: BMC pediatrics, 2026 Jun 10
PMID: 42265631
DOI: 10.1186/s12887-026-07095-9

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