Advancements in Dermatology: A Weekly Review
Dermatologia e Venerologia
Allergic to the Unexpected: Uncovering Hidden Triggers in Contact Dermatitis
This week we dive into the evolving science of contact allergies—from surprising findings on benzoyl peroxide sensitivity to the role of complement pathways across skin and mucosal barriers. Discover how everyday items like headphones may trigger reactions, why standardized allergy indexes matter, and how dupilumab is redefining treatment in complex cases. Tune in for a deep look at how immunology is reshaping dermatologic care.
Bibliography
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- Mose KF, Johansen JD, Simonsen AB, Schwensen JFB, Sommerlund M, Bregnhøj A, et al. Kontaktallergener [Contact allergens]. Ugeskr Laeger. 2025 Mar 31;187(14):V11240778. doi:10.61409/V11240778.
- Menanteau M, Fenech G, Adam B, Langlois E, Marcant P, Pelletier E, et al. Severe allergic contact dermatitis from octylisothiazolinone in over-ear headphones: a case series. Contact Dermatitis. 2025 Apr;92(4):291–8. doi:10.1111/cod.14733.
- Junge A, Radonjic-Hoesli S, Bossart S, Simon D, De Viragh P, Hunger RE, et al. Contact dermatitis caused by topical minoxidil: allergy or just irritation. Acta Derm Venereol. 2025 Apr 27;105:adv42401. doi:10.2340/actadv.v105.42401.
- Thomas SA, Lajoie S. Complement's involvement in allergic Th2 immunity: a cross-barrier perspective. J Clin Invest. 2025 May 1;135(9):e188352. doi:10.1172/JCI188352.
- Isufi D, Jensen MB, Kursawe Larsen C, Alinaghi F, Schwensen JFB, Johansen JD. Allergens responsible for contact allergy in children from 2010 to 2024: a systematic review and meta-analysis. Contact Dermatitis. 2025 May;92(5):327–43. doi:10.1111/cod.14753.
- Uter W, Andersen KE, Brans R, Bruze M, Schubert S, Gonçalo M, et al. The 'MOAHLFA(P) Index': an attempt to standardise a widely used array of descriptors of patch-tested patients. Contact Dermatitis. 2025 Apr;92(4):251–60. doi:10.1111/cod.14750.
- Mochizuki K, Takeoka J, Toda N, Otsuka K, Sato R, Kurahashi S, et al. A case of systemic contact dermatitis associated with a peritoneal dialysis catheter and treated with dupilumab. CEN Case Rep. 2025 Jun;14(3):450–4. doi:10.1007/s13730-025-00980-9.
- Asbell P, Akpek E, Chamberlain W, Chen Z, Lawless E, Van Spall M, et al. Conjunctivitis in adults with atopic dermatitis treated with dupilumab: an observational study of clinical characteristics, symptomatology, and treatment. Adv Ther. 2025 Jul;42(7):3285–305. doi:10.1007/s12325-025-03209-4.
- Tang HS, Ebriani J, Yan MJ, Wongvibulsin S, Farshchian M. Artificial intelligence in patch testing: comprehensive review of current applications and future prospects in dermatology. JMIR Dermatol. 2025 Jun 2;8:e67154. doi:10.2196/67154.
