Rethinking Diabetes: A Weekly Review
Malattie Metaboliche e Diabetologia
Advances in Diabetes and Metabolic Disorders
This week we discuss groundbreaking research in diabetes care, including novel treatments for MASH, weekly insulin options, hypoglycemia management strategies, and the latest in gestational diabetes and PCOS management.
Bibliography
1. A Phase 2 Randomized Trial of Survodutide in MASH and Fibrosis.
Authors: Sanyal AJ, Bedossa P, Fraessdorf M, et al.
Journal: The New England journal of medicine, 2024 Jul 25
PMID: 38847460
DOI: 10.1056/NEJMoa2401755
2. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy.
Authors: Brenner BM, Cooper ME, de Zeeuw D, et al.
Journal: The New England journal of medicine, 2001 Sep 20
PMID: 11565518
DOI: 10.1056/NEJMoa011161
3. Gestational Diabetes Mellitus: Diagnostic Approaches and Maternal-Offspring Complications.
Authors: Moon JH, Jang HC
Journal: Diabetes & metabolism journal, 2022 Jan
PMID: 35135076
DOI: 10.4093/dmj.2021.0335
4. Faricimab Treat-and-Extend for Diabetic Macular Edema: Two-Year Results from the Randomized Phase 3 YOSEMITE and RHINE Trials.
Authors: Wong TY, Haskova Z, Asik K, et al.
Journal: Ophthalmology, 2024 Jun
PMID: 38158159
DOI: 10.1016/j.ophtha.2023.12.026
5. Implementing sodium-glucose co-transporter 2 inhibitors in cardiovascular-kidney-metabolic syndrome: a multidisciplinary expert perspective.
Authors: Avogaro A, Gori M, Grandaliano G, et al.
Journal: European heart journal. Cardiovascular pharmacotherapy, 2026 May 19
PMID: 41968100
DOI: 10.1093/ehjcvp/pvag020
6. Once-Weekly Insulin Icodec vs Once-Daily Insulin Degludec in Adults With Insulin-Naive Type 2 Diabetes: The ONWARDS 3 Randomized Clinical Trial.
Authors: Lingvay I, Asong M, Desouza C, et al.
Journal: JAMA, 2023 Jul 18
PMID: 37354562
DOI: 10.1001/jama.2023.11313
7. Managing hypoglycaemia.
Authors: Iqbal A, Heller S
Journal: Best practice & research. Clinical endocrinology & metabolism, 2016 Jun
PMID: 27432075
DOI: 10.1016/j.beem.2016.06.004
8. The use of automated insulin delivery around physical activity and exercise in type 1 diabetes: a position statement of the European Association for the Study of Diabetes (EASD) and the International Society for Pediatric and Adolescent Diabetes (ISPAD).
Authors: Moser O, Zaharieva DP, Adolfsson P, et al.
Journal: Diabetologia, 2025 Feb
PMID: 39653802
DOI: 10.1007/s00125-024-06308-z
9. The latest reports and treatment methods on polycystic ovary syndrome.
Authors: Stańczak NA, Grywalska E, Dudzińska E
Journal: Annals of medicine, 2024 Dec
PMID: 38965663
DOI: 10.1080/07853890.2024.2357737
10. Combination scRNA-seq with GWAS identifies genetic risk factors in IgA nephropathy: An observational study.
Authors: Zhang J, Lu S, Liang G, et al.
Journal: Medicine, 2026 May 15
PMID: 42152401
DOI: 10.1097/MD.0000000000048751
Authors: Sanyal AJ, Bedossa P, Fraessdorf M, et al.
Journal: The New England journal of medicine, 2024 Jul 25
PMID: 38847460
DOI: 10.1056/NEJMoa2401755
2. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy.
Authors: Brenner BM, Cooper ME, de Zeeuw D, et al.
Journal: The New England journal of medicine, 2001 Sep 20
PMID: 11565518
DOI: 10.1056/NEJMoa011161
3. Gestational Diabetes Mellitus: Diagnostic Approaches and Maternal-Offspring Complications.
Authors: Moon JH, Jang HC
Journal: Diabetes & metabolism journal, 2022 Jan
PMID: 35135076
DOI: 10.4093/dmj.2021.0335
4. Faricimab Treat-and-Extend for Diabetic Macular Edema: Two-Year Results from the Randomized Phase 3 YOSEMITE and RHINE Trials.
Authors: Wong TY, Haskova Z, Asik K, et al.
Journal: Ophthalmology, 2024 Jun
PMID: 38158159
DOI: 10.1016/j.ophtha.2023.12.026
5. Implementing sodium-glucose co-transporter 2 inhibitors in cardiovascular-kidney-metabolic syndrome: a multidisciplinary expert perspective.
Authors: Avogaro A, Gori M, Grandaliano G, et al.
Journal: European heart journal. Cardiovascular pharmacotherapy, 2026 May 19
PMID: 41968100
DOI: 10.1093/ehjcvp/pvag020
6. Once-Weekly Insulin Icodec vs Once-Daily Insulin Degludec in Adults With Insulin-Naive Type 2 Diabetes: The ONWARDS 3 Randomized Clinical Trial.
Authors: Lingvay I, Asong M, Desouza C, et al.
Journal: JAMA, 2023 Jul 18
PMID: 37354562
DOI: 10.1001/jama.2023.11313
7. Managing hypoglycaemia.
Authors: Iqbal A, Heller S
Journal: Best practice & research. Clinical endocrinology & metabolism, 2016 Jun
PMID: 27432075
DOI: 10.1016/j.beem.2016.06.004
8. The use of automated insulin delivery around physical activity and exercise in type 1 diabetes: a position statement of the European Association for the Study of Diabetes (EASD) and the International Society for Pediatric and Adolescent Diabetes (ISPAD).
Authors: Moser O, Zaharieva DP, Adolfsson P, et al.
Journal: Diabetologia, 2025 Feb
PMID: 39653802
DOI: 10.1007/s00125-024-06308-z
9. The latest reports and treatment methods on polycystic ovary syndrome.
Authors: Stańczak NA, Grywalska E, Dudzińska E
Journal: Annals of medicine, 2024 Dec
PMID: 38965663
DOI: 10.1080/07853890.2024.2357737
10. Combination scRNA-seq with GWAS identifies genetic risk factors in IgA nephropathy: An observational study.
Authors: Zhang J, Lu S, Liang G, et al.
Journal: Medicine, 2026 May 15
PMID: 42152401
DOI: 10.1097/MD.0000000000048751
