Advancements in Gynecology: A Weekly Review
Ginecologia e Ostetricia
Iron Management in Pregnancy and Menopausal Sleep Solutions
This episode explores optimal iron management in pregnancy including IV iron therapy benefits, and examines evidence-based non-pharmacological solutions for menopausal insomnia. We also discuss a remarkable case of refractory TTP in twin pregnancy.
Bibliography
1. Pregnancy and iron: Bridging metabolic demands and supplementation needs.
Authors: Bedran M, Manceau H, Ollivier H, et al.
Journal: Clinical nutrition ESPEN, 2026 Oct
PMID: 42269928
DOI: 10.1016/j.clnesp.2026.103390
2. Pharmacological and non-pharmacological treatments for chronic insomnia in perimenopausal and postmenopausal women: a systematic review and meta-analysis.
Authors: Bruyneel M, Rozenberg S, Sanida C, et al.
Journal: Sleep medicine, 2026 Oct
PMID: 42247852
DOI: 10.1016/j.sleep.2026.109040
3. Systematic Review and Meta-Analysis: Plant-Based Therapy for Irritable Bowel Syndrome.
Authors: Meyer A, Auer J, Cascant-Ortolano L, et al.
Journal: Phytotherapy research : PTR, 2026 Oct
PMID: 42572206
DOI: 10.1002/ptr.70421
4. Rewiring the tumor microenvironment: IGFBP2 at the Nexus of remodeling and therapy resistance?
Authors: Das P, Conley SM, Panja P, et al.
Journal: Biochimica et biophysica acta. Reviews on cancer, 2026 Oct
PMID: 42546854
DOI: 10.1016/j.bbcan.2026.189672
5. Trained immunity in cancer immunotherapy and vaccine development: mechanisms, evidence gaps, and translational opportunities.
Authors: Yang L, Liu J, Zhang S, et al.
Journal: Frontiers in immunology, 2026
PMID: 42865883
DOI: 10.3389/fimmu.2026.1939256
6. Resistance to PD-1/PD-L1 blockade: Mechanism and pharmacological strategies.
Authors: Kim AMJ, Lee N, Chen HY, et al.
Journal: Pharmacological research, 2026 Oct
PMID: 42612932
DOI: 10.1016/j.phrs.2026.108404
7. Organelle-Selective Autophagy in Cancer Immunotherapy: Mitophagy and Nucleophagy-Related Nuclear Quality Control as Regulators of Tumor-Immune Interactions.
Authors: Bilir A, Yıldırım B, Karalök MH
Journal: International journal of molecular sciences, 2026 Sep 30
PMID: 42884017
DOI: 10.3390/ijms27198775
8. Antenatal Intravenous Iron Therapy in Anemic Pregnancies: Associations with Obstetric Patient Blood Management and Neonatal Outcomes.
Authors: Romani E, Parisi F, Zullino S, et al.
Journal: Nutrients, 2026 Sep 26
PMID: 42884621
DOI: 10.3390/nu18193169
9. Dynamic metabolic programming of monocyte-derived cells defines immunity in CNS disease.
Authors: Wishart CL, Tan J, King NJC
Journal: Brain : a journal of neurology, 2026 Oct 5
PMID: 42052880
DOI: 10.1093/brain/awag149
10. Refractory Acquired Thrombotic Thrombocytopenic Purpura in the Third Trimester of Twin Pregnancy: A Case Report.
Authors: Jawahar Kanth JS, Okello MO, Anish TMR, et al.
Journal: International medical case reports journal, 2026
PMID: 42829733
DOI: 10.2147/IMCRJ.S629280
Authors: Bedran M, Manceau H, Ollivier H, et al.
Journal: Clinical nutrition ESPEN, 2026 Oct
PMID: 42269928
DOI: 10.1016/j.clnesp.2026.103390
2. Pharmacological and non-pharmacological treatments for chronic insomnia in perimenopausal and postmenopausal women: a systematic review and meta-analysis.
Authors: Bruyneel M, Rozenberg S, Sanida C, et al.
Journal: Sleep medicine, 2026 Oct
PMID: 42247852
DOI: 10.1016/j.sleep.2026.109040
3. Systematic Review and Meta-Analysis: Plant-Based Therapy for Irritable Bowel Syndrome.
Authors: Meyer A, Auer J, Cascant-Ortolano L, et al.
Journal: Phytotherapy research : PTR, 2026 Oct
PMID: 42572206
DOI: 10.1002/ptr.70421
4. Rewiring the tumor microenvironment: IGFBP2 at the Nexus of remodeling and therapy resistance?
Authors: Das P, Conley SM, Panja P, et al.
Journal: Biochimica et biophysica acta. Reviews on cancer, 2026 Oct
PMID: 42546854
DOI: 10.1016/j.bbcan.2026.189672
5. Trained immunity in cancer immunotherapy and vaccine development: mechanisms, evidence gaps, and translational opportunities.
Authors: Yang L, Liu J, Zhang S, et al.
Journal: Frontiers in immunology, 2026
PMID: 42865883
DOI: 10.3389/fimmu.2026.1939256
6. Resistance to PD-1/PD-L1 blockade: Mechanism and pharmacological strategies.
Authors: Kim AMJ, Lee N, Chen HY, et al.
Journal: Pharmacological research, 2026 Oct
PMID: 42612932
DOI: 10.1016/j.phrs.2026.108404
7. Organelle-Selective Autophagy in Cancer Immunotherapy: Mitophagy and Nucleophagy-Related Nuclear Quality Control as Regulators of Tumor-Immune Interactions.
Authors: Bilir A, Yıldırım B, Karalök MH
Journal: International journal of molecular sciences, 2026 Sep 30
PMID: 42884017
DOI: 10.3390/ijms27198775
8. Antenatal Intravenous Iron Therapy in Anemic Pregnancies: Associations with Obstetric Patient Blood Management and Neonatal Outcomes.
Authors: Romani E, Parisi F, Zullino S, et al.
Journal: Nutrients, 2026 Sep 26
PMID: 42884621
DOI: 10.3390/nu18193169
9. Dynamic metabolic programming of monocyte-derived cells defines immunity in CNS disease.
Authors: Wishart CL, Tan J, King NJC
Journal: Brain : a journal of neurology, 2026 Oct 5
PMID: 42052880
DOI: 10.1093/brain/awag149
10. Refractory Acquired Thrombotic Thrombocytopenic Purpura in the Third Trimester of Twin Pregnancy: A Case Report.
Authors: Jawahar Kanth JS, Okello MO, Anish TMR, et al.
Journal: International medical case reports journal, 2026
PMID: 42829733
DOI: 10.2147/IMCRJ.S629280
